There is no single comprehensive dataset, but available research gives rough orders of magnitude for wrongful arrest/conviction generally and for wrongful immigration detention/deportation of U.S. citizens in particular.[1][2]

Wrongful arrest/conviction of citizens (domestic criminal system)

There are no official federal statistics on how many arrests are wrongful (i.e., no legal basis or wrong person), but there is better data on wrongful convictions and exonerations.

These figures cover wrongful convictions, not all wrongful arrests; since many wrongful arrests never result in conviction, the number of people wrongfully arrested each year is necessarily larger, but not well quantified in national data.[6][3]

Wrongful immigration arrest/detention of U.S. citizens

Here the data are sparse and fragmented, but multiple investigations show that U.S. citizens are repeatedly swept into the immigration-enforcement system.

These figures suggest that, in a typical recent year, dozens to hundreds of U.S. citizens are arrested or detained in immigration operations, with a smaller (but non‑trivial) subset actually deported before the error is corrected.[8][2]

How often are citizens actually deported by mistake?

The clearest quantitative window is the GAO period (2015–2020):